BD-PT2481-KKIALRE Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

KKIALRE Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT2481

产品名称

KKIALRE Rabbit Polyclonal Antibody

别名

CDKL1; Cyclin-dependent kinase-like 1; Protein kinase p42 KKIALRE; Serine/threonine-protein kinase KKIALRE

类别

常规抗体

基因名称

CDKL1

蛋白名称

Cyclin-dependent kinase-like 1

推荐应用

反应种属

Human,Rat

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

8814

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8814

Human Swissprot No.

Q00532

Human Swissprot Link

http://www.uniprot.org/uniprotkb/Q00532/entry

Mouse Swissprot No.

Q8CEQ0

Mouse Swissprot Link

http://www.uniprot.org/uniprot/Q8CEQ0

Rat Gene ID

314198

Rat Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=314198

Rat Swissprot No.

Q66HE7

Rat Swissprot Link

http://www.uniprot.org/uniprot/Q66HE7

免疫原

The antiserum was produced against synthesized peptide derived from human CDKL1. AA range:281-330

特异性

KKIALRE Polyclonal Antibody detects endogenous levels of KKIALRE protein.

稀释度

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

预测分子量

42kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013],

组织表达

Highly expressed in kidney, and to a lower extent in ovary.

细胞定位

Cytoplasm . Nucleus .

功能

catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The [NKR]KIAxRE motif seems to be a cyclin-binding region.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Highly expressed in kidney, and to a lower extent in ovary.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from COLO205 cells, using CDKL1 Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of the lysates from COLO205 cells using CDKL1 antibody.

Western Blot analysis of various cells using KKIALRE Polyclonal Antibody diluted at 1：500

Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100（4°,overnight）. High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl （right） obtaned from antibody was pre-absorbed by immunogen peptide.