产品名称
KCNF1 Rabbit Polyclonal Antibody
别名
KCNF1; Potassium voltage-gated channel subfamily F member 1; Voltage-gated potassium channel subunit Kv5.1; kH1
蛋白名称
Potassium voltage-gated channel subfamily F member 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3754
Human Swissprot No.
Q9H3M0
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9H3M0/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=382571
Mouse Swissprot No.
Q7TSH7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q7TSH7
免疫原
The antiserum was produced against synthesized peptide derived from human KCNF1. AA range:191-240
特异性
KCNF1 Polyclonal Antibody detects endogenous levels of KCNF1 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily F. This gene is intronless and expressed in all tissues tested, including the heart, skeletal muscle, brain, kidney, and pancreas. [provided by RefSeq, Jul 2008],
组织表达
Detected in heart, brain, liver, skeletal muscle, kidney and pancreas.
细胞定位
Membrane; Multi-pass membrane protein.
功能
domain:The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.,function:Putative voltage-gated potassium channel.,similarity:Belongs to the potassium channel family. F subfamily.,subunit:Heteromultimer with KCNG3, KCNG4 and KCNV2. Interacts with DLG1.,tissue specificity:Detected in heart, brain, liver, skeletal muscle, kidney and pancreas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
