产品名称
Jun D Rabbit Polyclonal Antibody
别名
JUND; Transcription factor jun-D
蛋白名称
Transcription factor jun-D
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3727
Human Swissprot No.
P17535
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P17535/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=16478
Mouse Swissprot No.
P15066
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P15066
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24518
Rat Swissprot Link
http://www.uniprot.org/uniprot/P52909
免疫原
The antiserum was produced against synthesized peptide derived from human JunD. AA range:222-271
特异性
Jun D Polyclonal Antibody detects endogenous levels of Jun D protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. Immunoprecipitation: 2-5 ug:mg lysate. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216). [provided by RefSeq, Nov 2013],
信号通路
MAPK_ERK_Growth;MAPK_G_Protein;
功能
function:Binds an AP-1 site and upon cotransfection stimulates the activity of a promoter that bears an AP-1 site.,similarity:Belongs to the bZIP family. Jun subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
