产品名称
IPMK Rabbit Polyclonal Antibody
别名
IPMK; IMPK; Inositol polyphosphate multikinase; Inositol 1; 3,4,6-tetrakisphosphate 5-kinase
蛋白名称
Inositol polyphosphate multikinase
反应种属
Human,Mouse,Rat,Monkey
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=253430
Human Swissprot No.
Q8NFU5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8NFU5/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=69718
Mouse Swissprot No.
Q7TT16
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q7TT16
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=171458
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q99NI4
免疫原
The antiserum was produced against synthesized peptide derived from human IPMK. AA range:311-360
特异性
IPMK Polyclonal Antibody detects endogenous levels of IPMK protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the inositol phosphokinase family. The encoded protein has 3-kinase, 5-kinase and 6-kinase activities on phosphorylated inositol substrates. The encoded protein plays an important role in the biosynthesis of inositol 1,3,4,5,6-pentakisphosphate, and has a preferred 5-kinase activity. This gene may play a role in nuclear mRNA export. Pseudogenes of this gene are located on the long arm of chromosome 13 and the short arm of chromosome 19. [provided by RefSeq, Dec 2010],
组织表达
Ubiquitous, with the highest expression in skeletal muscle, liver, placenta, lung, peripheral blood leukocytes, kidney, spleen and colon.
信号通路
Inositol phosphate metabolism;
功能
catalytic activity:ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate.,catalytic activity:ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate.,function:Inositol phosphate kinase with a broad substrate specificity. Has a preference for inositol-1,4,5-trisphosphate (Ins(1,4,5)P3) and inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4).,similarity:Belongs to the inositol phosphokinase (IPK) family.,tissue specificity:Ubiquitous, with the highest expression in skeletal muscle, liver, placenta, lung, peripheral blood leukocytes, kidney, spleen and colon.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
