BD-PT2382-IP6K2 Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

IP6K2 Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT2382

产品名称

IP6K2 Rabbit Polyclonal Antibody

别名

IP6K2; IHPK2; TCCCIA00113; Inositol hexakisphosphate kinase 2; InsP6 kinase 2; P(i)-uptake stimulator; PiUS

类别

常规抗体

基因名称

IP6K2

蛋白名称

Inositol hexakisphosphate kinase 2

推荐应用

反应种属

Human,Mouse,Rat

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

51447

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51447

Human Swissprot No.

Q9UHH9

Human Swissprot Link

http://www.uniprot.org/uniprotkb/Q9UHH9/entry

Mouse Gene ID

76500

Mouse Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=76500

Mouse Swissprot No.

Q80V72

Mouse Swissprot Link

http://www.uniprot.org/uniprot/Q80V72

Rat Gene ID

59268

Rat Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=59268

Rat Swissprot No.

Q9R0U1

Rat Swissprot Link

http://www.uniprot.org/uniprot/Q9R0U1

免疫原

The antiserum was produced against synthesized peptide derived from human IP6K2. AA range:161-210

特异性

IP6K2 Polyclonal Antibody detects endogenous levels of IP6K2 protein.

稀释度

WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

预测分子量

49kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

组织表达

Caudate nucleus,Glial tumor,Leukemia,Lung,Skin,Uterus,

细胞定位

Nucleus .

功能

catalytic activity:ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate (isomeric configuration unknown).,catalytic activity:ATP + 1D-myo-inositol hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate.,function:Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.,similarity:Belongs to the inositol phosphokinase (IPK) family.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunofluorescence analysis of COS7 cells, using IP6K2 Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from HUVEC, COLO, and Jurkat cells, using IP6K2 Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of the lysates from K562 cells using IP6K2 antibody.

Western Blot analysis of various cells using IP6K2 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit （SC-003,Inventbiotech,MN,USA）.

Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100（4°,overnight）. High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl （right） obtaned from antibody was pre-absorbed by immunogen peptide.