BD-PT2380

IP3KA Rabbit Polyclonal Antibody

ITPKA; Inositol-trisphosphate 3-kinase A; Inositol 1; 4,5-trisphosphate 3-kinase A; IP3 3-kinase A; IP3K A; InsP 3-kinase A

常规抗体

ITPKA

Inositol-trisphosphate 3-kinase A

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

3706

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3706

P23677

http://www.uniprot.org/uniprotkb/P23677/entry

228550

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=228550

Q8R071

http://www.uniprot.org/uniprot/Q8R071

81677

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=81677

P17105

http://www.uniprot.org/uniprot/P17105

The antiserum was produced against synthesized peptide derived from human IP3KA. AA range:396-445

IP3KA Polyclonal Antibody detects endogenous levels of IP3KA protein.

WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000

52kD

-20°C/1 year

Polyclonal, Rabbit,IgG

Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.[provided by RefSeq, Apr 2011],

Expressed in brain.

Cytoplasm, cytoskeleton .

Inositol phosphate metabolism;Calcium;Phosphatidylinositol signaling system;

catalytic activity:ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate.,enzyme regulation:IP3K is activated by calmodulin.,similarity:Belongs to the inositol phosphokinase (IPK) family.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.