产品名称
Inhibin β-C Rabbit Polyclonal Antibody
别名
INHBC; Inhibin beta C chain; Activin beta-C chain
蛋白名称
Inhibin beta C chain
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3626
Human Swissprot No.
P55103
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P55103/entry
Mouse Swissprot No.
P55104
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P55104
免疫原
The antiserum was produced against synthesized peptide derived from human Inhibin beta-C. AA range:80-129
特异性
Inhibin β-C Polyclonal Antibody detects endogenous levels of Inhibin β-C protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of homodimeric and heterodimeric activin complexes. The heterodimeric complex may function in the inhibition of activin A signaling. Transgenic mice overexpressing this gene exhibit defects in testis, liver and prostate. [provided by RefSeq, Aug 2016],
组织表达
Expressed in benign prostatic hyperplasia.
信号通路
Cytokine-cytokine receptor interaction;TGF-beta;
功能
function:Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.,similarity:Belongs to the TGF-beta family.,subunit:Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.,tissue specificity:Expressed in benign prostatic hyperplasia.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
