产品名称
IL-32 Rabbit Polyclonal Antibody
别名
IL32; NK4; TAIF; Interleukin-32; IL-32; Natural killer cells protein 4; Tumor necrosis factor alpha-inducing factor
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9235
Human Swissprot No.
P24001
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P24001/entry
免疫原
The antiserum was produced against synthesized peptide derived from human IL-32. AA range:177-226
特异性
IL-32 Polyclonal Antibody detects endogenous levels of IL-32 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
组织表达
Selectively expressed in lymphocytes. Expression is more prominent in immune cells than in non-immune cells.
功能
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK.,induction:Expression increased after activation of T-cells by mitogens or activation of NK cells by IL-2.,tissue specificity:Selectively expressed in lymphocytes. Expression more prominent in immunce cells than in non-immune cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
