产品名称
IL-20Rβ Rabbit Polyclonal Antibody
别名
IL20RB; DIRS1; Interleukin-20 receptor subunit beta; IL-20 receptor subunit beta; IL-20R-beta; IL-20RB; IL-20R2
蛋白名称
Interleukin-20 receptor subunit beta
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=53833
Human Swissprot No.
Q6UXL0
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q6UXL0/entry
免疫原
The antiserum was produced against synthesized peptide derived from human IL20RB. AA range:141-190
特异性
IL-20Rβ Polyclonal Antibody detects endogenous levels of IL-20Rβ protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20 (IL20; MIM 605619) (Blumberg et al., 2001 [PubMed 11163236]).[supplied by OMIM, Feb 2009],
组织表达
Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin.
细胞定位
Membrane ; Single-pass type I membrane protein .
信号通路
Cytokine-cytokine receptor interaction;Jak_STAT;
功能
function:The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.,similarity:Belongs to the type II cytokine receptor family.,similarity:Contains 2 fibronectin type-III domains.,subunit:Heterodimer with IL20RA and heterodimer with IL22RA1.,tissue specificity:Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
