产品名称
IGSF4D Rabbit Polyclonal Antibody
别名
CADM2; IGSF4D; NECL3; Cell adhesion molecule 2; Immunoglobulin superfamily member 4D; IgSF4D; Nectin-like protein 3; NECL-3; Synaptic cell adhesion molecule 2; SynCAM 2
蛋白名称
Cell adhesion molecule 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=253559
Human Swissprot No.
Q8N3J6
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8N3J6/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=239857
Mouse Swissprot No.
Q8BLQ9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BLQ9
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=360687
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q1WIM2
免疫原
The antiserum was produced against synthesized peptide derived from human CADM2. AA range:131-180
特异性
IGSF4D Polyclonal Antibody detects endogenous levels of IGSF4D protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
cell adhesion molecule 2(CADM2) Homo sapiens This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4.1 binding site near the C-terminus. Proteins belonging to the protein 4.1 family crosslink spectrin and interact with other cytoskeletal proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012],
组织表达
Amygdala,Brain,Stomach,
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse . Cell projection, axon . Found in the axoplasm of myelinated axons.
功能
similarity:Belongs to the nectin family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
