产品名称
IFITM3 Rabbit Polyclonal Antibody
别名
IFITM3; Interferon-induced transmembrane protein 3; Dispanin subfamily A member 2b; DSPA2b; Interferon-inducible protein 1-8U
蛋白名称
Interferon-induced transmembrane protein 3
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10410
Human Swissprot No.
Q01628
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q01628/entry
Mouse Swissprot No.
Q9CQW9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CQW9
免疫原
The antiserum was produced against synthesized peptide derived from human IFM3. AA range:1-50
特异性
IFITM3 Polyclonal Antibody detects endogenous levels of IFITM3 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus, and dengue virus. Two transcript variants, only one of them protein-coding, have been found for this gene. Another variant encoding an N-terminally truncated isoform has been reported, but the full-length nature of this variant has not been determined. [provided by RefSeq, May 2012],
组织表达
Brain,Cervix,Vascular endothelial cell,
细胞定位
Cell membrane ; Single-pass type II membrane protein . Late endosome membrane ; Single-pass type II membrane protein . Early endosome membrane ; Single-pass type II membrane protein. Lysosome membrane ; Single-pass type II membrane protein . Cytoplasm, perinuclear region . Co-localizes with BRI3 isoform 1 at the perinuclear region. .
功能
induction:By alpha and gamma interferons.,similarity:Belongs to the CD225 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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