产品名称
IF3 Rabbit Polyclonal Antibody
别名
MTIF3; DC38; Translation initiation factor IF-3; mitochondrial; IF-3(Mt); IF-3Mt; IF3(mt); IF3mt
蛋白名称
Translation initiation factor IF-3 mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=219402
Human Swissprot No.
Q9H2K0
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9H2K0/entry
Mouse Swissprot No.
Q9CZD5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CZD5
免疫原
The antiserum was produced against synthesized peptide derived from human MTIF3. AA range:69-118
特异性
IF3 Polyclonal Antibody detects endogenous levels of IF3 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a translation initiation factor that is involved in mitochondrial protein synthesis. Polymorphism in this gene is associated with the onset of Parkinson's disease. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Oct 2009],
组织表达
Cervix,Colon,Dendritic cell,Melanocyte,
功能
function:IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins.,similarity:Belongs to the IF-3 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
