产品名称
HuB/D Rabbit Polyclonal Antibody
别名
ELAVL2; HUB; ELAV-like protein 2; ELAV-like neuronal protein 1; Hu-antigen B; HuB; Nervous system-specific RNA-binding protein Hel-N1; ELAVL4; HUD; PNEM; ELAV-like protein 4; Hu-antigen D; HuD; Paraneoplastic encephalomyelitis antigen HuD
蛋白名称
ELAV-like protein 2/ELAV-like protein 4
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1993
Human Swissprot No.
Q12926/P26378
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q12926/entry
Mouse Gene ID
15569/15572
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15569
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=432358
Rat Swissprot No.
Q8CH84/O09032
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q8CH84
免疫原
The antiserum was produced against synthesized peptide derived from human ELAV2/4. AA range:61-110
特异性
HuB/D Polyclonal Antibody detects endogenous levels of HuB/D protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
ELAV like RNA binding protein 2(ELAVL2) Homo sapiens The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],
组织表达
Brain; neural-specific.
功能
function:Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.,similarity:Belongs to the RRM elav family.,similarity:Contains 3 RRM (RNA recognition motif) domains.,tissue specificity:Brain; neural-specific.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
