产品名称
HSP10 Rabbit Polyclonal Antibody
别名
HSPE1; 10 kDa heat shock protein; mitochondrial; Hsp10; 10 kDa chaperonin; Chaperonin 10; CPN10; Early-pregnancy factor; EPF
蛋白名称
10 kDa heat shock protein mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3336
Human Swissprot No.
P61604
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P61604/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15528
Mouse Swissprot No.
Q64433
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q64433
Rat Swissprot Link
http://www.uniprot.org/uniprot/P26772
免疫原
The antiserum was produced against synthesized peptide derived from human HSP10. AA range:51-100
特异性
HSP10 Polyclonal Antibody detects endogenous levels of HSP10 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.[provided by RefSeq, Feb 2011],
组织表达
B-cell lymphoma,Uterus,
细胞定位
Mitochondrion matrix.
功能
function:Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.,induction:By stress.,mass spectrometry: PubMed:7912672,similarity:Belongs to the groES chaperonin family.,subunit:Homohexamer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
