产品名称
HSP A9 Rabbit Polyclonal Antibody
别名
HSPA9; GRP75; HSPA9B; Stress-70 protein; mitochondrial; 75 kDa glucose-regulated protein; GRP-75; Heat shock 70 kDa protein 9; Mortalin; MOT; Peptide-binding protein 74; PBP74
蛋白名称
Stress-70 protein mitochondrial
反应种属
Human,Mouse,Rat,Monkey
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3313
Human Swissprot No.
P38646/Q8N1C8
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P38646/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15526
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=291671
Rat Swissprot Link
http://www.uniprot.org/uniprot/P48721
免疫原
The antiserum was produced against synthesized peptide derived from human GRP75. AA range:630-679
特异性
HSP A9 Polyclonal Antibody detects endogenous levels of HSP A9 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.[provided by RefSeq, May 2010],
组织表达
B-cell,Brain,Cajal-Retzius cell,Colon carcinoma,Fetal brain
细胞定位
Mitochondrion . Nucleus, nucleolus .
功能
function:Implicated in the control of cell proliferation and cellular aging. May also act as a chaperone.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with FXN.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
.jpg)
