产品名称
HSF2 Rabbit Polyclonal Antibody
别名
HSF2; HSTF2; Heat shock factor protein 2; HSF 2; Heat shock transcription factor 2; HSTF 2
蛋白名称
Heat shock factor protein 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3298
Human Swissprot No.
Q03933
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q03933/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15500
Mouse Swissprot No.
P38533
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P38533
免疫原
The antiserum was produced against synthesized peptide derived from human HSF2. AA range:401-450
特异性
HSF2 Polyclonal Antibody detects endogenous levels of HSF2 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
heat shock transcription factor 2(HSF2) Homo sapiens The protein encoded by this gene belongs to the HSF family of transcription factors that bind specifically to the heat-shock promoter element and activate transcription. Heat shock transcription factors activate heat-shock response genes under conditions of heat or other stresses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011],
组织表达
Bladder,Brain,PCR rescued clones,Testis,
细胞定位
Cytoplasm . Nucleus . Cytoplasmic during normal growth and moves to the nucleus upon activation.
功能
function:DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.,similarity:Belongs to the HSF family.,subcellular location:Cytoplasmic during normal growth and moves to the nucleus upon activation.,subunit:DNA-binding homotrimer in stressed or heat shocked cells, otherwise found as a homodimer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
