产品名称
Hox-A7 Rabbit Polyclonal Antibody
别名
HOXA7; HOX1A; Homeobox protein Hox-A7; Homeobox protein Hox 1.1; Homeobox protein Hox-1A
蛋白名称
Homeobox protein Hox-A7
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3204
Human Swissprot No.
P31268
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P31268/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15404
Mouse Swissprot No.
P02830
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P02830
Rat Swissprot Link
http://www.uniprot.org/uniprot/P09634
免疫原
The antiserum was produced against synthesized peptide derived from human HOXA7. AA range:91-140
特异性
Hox-A7 Polyclonal Antibody detects endogenous levels of Hox-A7 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. For example, the encoded protein represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression is then overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of Drosophila. [provided by RefSeq, Jul 2008],
功能
function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.,similarity:Belongs to the Antp homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.