BD-PT2204-hnRNP LL Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

hnRNP LL Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT2204

产品名称

hnRNP LL Rabbit Polyclonal Antibody

别名

HNRPLL; SRRF; BLOCK24; Heterogeneous nuclear ribonucleoprotein L-like; hnRNPLL; Stromal RNA-regulating factor

类别

常规抗体

基因名称

HNRPLL

蛋白名称

Heterogeneous nuclear ribonucleoprotein L-like

推荐应用

反应种属

Human,Mouse,Rat

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

92906

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=92906

Human Swissprot No.

Q8WVV9

Human Swissprot Link

http://www.uniprot.org/uniprotkb/Q8WVV9/entry

Mouse Gene ID

72692

Mouse Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=72692

Mouse Swissprot No.

Q921F4

Mouse Swissprot Link

http://www.uniprot.org/uniprot/Q921F4

免疫原

The antiserum was produced against synthesized peptide derived from human HNRPLL. AA range:241-290

特异性

hnRNP LL Polyclonal Antibody detects endogenous levels of hnRNP LL protein.

稀释度

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

预测分子量

60kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

heterogeneous nuclear ribonucleoprotein L like(HNRNPLL) Homo sapiens HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008],

组织表达

Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung.

细胞定位

nucleus,membrane,viral nucleocapsid,intracellular ribonucleoprotein complex,

功能

function:May bind RNA and play a role in mRNA processing.,similarity:Contains 3 RRM (RNA recognition motif) domains.,tissue specificity:Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from HUVEC and COLO cells, using HNRPLL Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using hnRNP LL Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit （SC-003,Inventbiotech,MN,USA）.

Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100（4°,overnight）. High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl （right） obtaned from antibody was pre-absorbed by immunogen peptide.