产品名称
Hox-A7 Rabbit Polyclonal Antibody
别名
HOXA7; HOX1A; Homeobox protein Hox-A7; Homeobox protein Hox 1.1; Homeobox protein Hox-1A
蛋白名称
Homeobox protein Hox-A7
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3204
Human Swissprot No.
P31268
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P31268/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15404
Mouse Swissprot No.
P02830
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P02830
Rat Swissprot Link
http://www.uniprot.org/uniprot/P09634
免疫原
The antiserum was produced against synthesized peptide derived from human HOXA7. AA range:91-140
特异性
Hox-A7 Polyclonal Antibody detects endogenous levels of Hox-A7 protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. For example, the encoded protein represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression is then overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of Drosophila. [provided by RefSeq, Jul 2008],
功能
function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.,similarity:Belongs to the Antp homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.