BD-PC0052

Cleaved-Ephrin-A2 (N188) Rabbit Polyclonal Antibody

EFNA2; EPLG6; LERK6; Ephrin-A2; EPH-related receptor tyrosine kinase ligand 6; LERK-6; HEK7 ligand; HEK7-L

常规抗体

EFNA2

Ephrin-A2

WB

Human,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

1943

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1943

O43921

http://www.uniprot.org/uniprotkb/O43921/entry

13637

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13637

P52801

http://www.uniprot.org/uniprot/P52801

The antiserum was produced against synthesized peptide derived from human EFNA2. AA range:139-188

Cleaved-Ephrin-A2 (N188) Polyclonal Antibody detects endogenous levels of fragment of activated Ephrin-A2 protein resulting from cleavage adjacent to N188.

WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

21kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm. [provided by RefSeq, Jul 2008],

Brain,

Cell membrane ; Lipid-anchor, GPI-anchor .

Axon guidance;

similarity:Belongs to the ephrin family.,subunit:Binds to the receptor tyrosine kinases EPHA3, EPHA4 and EPHA5.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.