产品名称
HLX1 Rabbit Polyclonal Antibody
别名
HLX; HLX1; H2.0-like homeobox protein; Homeobox protein HB24; Homeobox protein HLX1
蛋白名称
H2.0-like homeobox protein
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3142
Human Swissprot No.
Q14774
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q14774/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15284
Mouse Swissprot No.
Q61670
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q61670
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=364069
Rat Swissprot Link
http://www.uniprot.org/uniprot/A0JPN1
免疫原
The antiserum was produced against synthesized peptide derived from human HLX1. AA range:321-370
特异性
HLX1 Polyclonal Antibody detects endogenous levels of HLX1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis.,sequence caution:Translation N-terminally extended.,similarity:Belongs to the H2.0 homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.,
组织表达
Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.
功能
function:Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis.,sequence caution:Translation N-terminally extended.,similarity:Belongs to the H2.0 homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
