产品名称
Hepatic Lipase Rabbit Polyclonal Antibody
别名
LIPC; HTGL; Hepatic triacylglycerol lipase; HL; Hepatic lipase; Lipase member C
蛋白名称
Hepatic triacylglycerol lipase
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3990
Human Swissprot No.
P11150
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P11150/entry
Mouse Swissprot No.
P27656
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P27656
免疫原
The antiserum was produced against synthesized peptide derived from human LIPC. AA range:301-350
特异性
Hepatic Lipase Polyclonal Antibody detects endogenous levels of Hepatic Lipase protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
LIPC encodes hepatic triglyceride lipase, which is expressed in liver. LIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. [provided by RefSeq, Jul 2008],
组织表达
Donated clones,Liver,Thymus,
信号通路
Glycerolipid metabolism;
功能
catalytic activity:Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.,disease:Defects in LIPC are the cause of hepatic lipase deficiency (HL deficiency) [MIM:151670].,function:Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin.,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the AB hydrolase superfamily. Lipase family.,similarity:Contains 1 PLAT domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
