产品名称
Hel-N1 Rabbit Polyclonal Antibody
别名
ELAVL2; HUB; ELAV-like protein 2; ELAV-like neuronal protein 1; Hu-antigen B; HuB; Nervous system-specific RNA-binding protein Hel-N1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1993
Human Swissprot No.
Q12926
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q12926/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15569
Mouse Swissprot No.
Q60899
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q60899
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q8CH84
免疫原
The antiserum was produced against synthesized peptide derived from human ELAVL2. AA range:11-60
特异性
Hel-N1 Polyclonal Antibody detects endogenous levels of Hel-N1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
ELAV like RNA binding protein 2(ELAVL2) Homo sapiens The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],
组织表达
Brain; neural-specific.
功能
function:Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.,similarity:Belongs to the RRM elav family.,similarity:Contains 3 RRM (RNA recognition motif) domains.,tissue specificity:Brain; neural-specific.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.