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Helios Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT2123
产品名称
Helios Rabbit Polyclonal Antibody
别名
IKZF2; HELIOS; ZNFN1A2; Zinc finger protein Helios; Ikaros family zinc finger protein 2
类别
常规抗体
基因名称
IKZF2
蛋白名称
Zinc finger protein Helios
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
22807
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22807
Human Swissprot No.
Q9UKS7
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9UKS7/entry
Mouse Gene ID
22779
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22779
Mouse Swissprot No.
P81183
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P81183
免疫原
The antiserum was produced against synthesized peptide derived from human IKZF2. AA range:331-380
特异性
Helios Polyclonal Antibody detects endogenous levels of Helios protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
预测分子量
56kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008],
组织表达
Epithelium,Testis,
细胞定位
Nucleus .
功能
function:Associates with Ikaros at centromeric heterochromatin.,similarity:Belongs to the Ikaros C2H2-type zinc-finger protein family.,similarity:Contains 6 C2H2-type zinc fingers.,subunit:Interacts with IKZF4 AND IKZF5.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of the lysates from HeLa cells using IKZF2 antibody.

Western Blot analysis of Hela cells using Helios Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

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