产品名称
Helios Rabbit Polyclonal Antibody
别名
IKZF2; HELIOS; ZNFN1A2; Zinc finger protein Helios; Ikaros family zinc finger protein 2
蛋白名称
Zinc finger protein Helios
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22807
Human Swissprot No.
Q9UKS7
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9UKS7/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22779
Mouse Swissprot No.
P81183
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P81183
免疫原
The antiserum was produced against synthesized peptide derived from human IKZF2. AA range:331-380
特异性
Helios Polyclonal Antibody detects endogenous levels of Helios protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008],
功能
function:Associates with Ikaros at centromeric heterochromatin.,similarity:Belongs to the Ikaros C2H2-type zinc-finger protein family.,similarity:Contains 6 C2H2-type zinc fingers.,subunit:Interacts with IKZF4 AND IKZF5.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.