产品名称
Cleaved-Cathepsin Z (L62) Rabbit Polyclonal Antibody
别名
CTSZ; Cathepsin Z; Cathepsin P; Cathepsin X
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1522
Human Swissprot No.
Q9UBR2
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9UBR2/entry
Mouse Swissprot No.
Q9WUU7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9WUU7
免疫原
The antiserum was produced against synthesized peptide derived from human CATZ. AA range:43-92
特异性
Cleaved-Cathepsin Z (L62) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin Z protein resulting from cleavage adjacent to L62.
稀释度
WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis. [provided by RefSeq, Oct 2008],
功能
catalytic activity:Release of C-terminal amino acid residues with broad specificity, but lacks action on C-terminal proline. Shows weak endopeptidase activity.,function:Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity.,similarity:Belongs to the peptidase C1 family.,tissue specificity:Widely expressed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
