产品名称
Hepatic Lipase Rabbit Polyclonal Antibody
别名
LIPC; HTGL; Hepatic triacylglycerol lipase; HL; Hepatic lipase; Lipase member C
蛋白名称
Hepatic triacylglycerol lipase
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3990
Human Swissprot No.
P11150
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P11150/entry
Mouse Swissprot No.
P27656
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P27656
免疫原
The antiserum was produced against synthesized peptide derived from human LIPC. AA range:301-350
特异性
Hepatic Lipase Polyclonal Antibody detects endogenous levels of Hepatic Lipase protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
LIPC encodes hepatic triglyceride lipase, which is expressed in liver. LIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. [provided by RefSeq, Jul 2008],
组织表达
Donated clones,Liver,Thymus,
信号通路
Glycerolipid metabolism;
功能
catalytic activity:Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.,disease:Defects in LIPC are the cause of hepatic lipase deficiency (HL deficiency) [MIM:151670].,function:Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin.,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the AB hydrolase superfamily. Lipase family.,similarity:Contains 1 PLAT domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
