产品名称
hCAP-G2 Rabbit Polyclonal Antibody
别名
NCAPG2; LUZP5; Condensin-2 complex subunit G2; Chromosome-associated protein G2; CAP-G2; hCAP-G2; Leucine zipper protein 5; Non-SMC condensin II complex subunit G2
蛋白名称
Condensin-2 complex subunit G2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54892
Human Swissprot No.
Q86XI2
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q86XI2/entry
Mouse Swissprot No.
Q6DFV1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6DFV1
免疫原
The antiserum was produced against synthesized peptide derived from human NCAPG2. AA range:561-610
特异性
hCAP-G2 Polyclonal Antibody detects endogenous levels of hCAP-G2 protein.
稀释度
WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:40000. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
non-SMC condensin II complex subunit G2(NCAPG2) Homo sapiens This gene encodes a protein that belongs to the Condensin2nSMC family of proteins. The encoded protein is a regulatory subunit of the condensin II complex which, along with the condensin I complex, plays a role in chromosome assembly and segregation during mitosis. A similar protein in mouse is required for early development of the embryo. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],
组织表达
Endometrium,Epithelium,Ovary,Testis,
功能
function:Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.,similarity:Contains 1 HEAT repeat.,subunit:Component of the condensin-2 complex, which contains the SMC2 and SMC4 heterodimer, and 3 non SMC subunits that probably regulate the complex: NCAPH2, NCAPD3 and NCAPG2.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
