BD-PT2093

Gα olf Rabbit Polyclonal Antibody

GNAL; Guanine nucleotide-binding protein G(olf) subunit alpha; Adenylate cyclase-stimulating G alpha protein; olfactory type

常规抗体

GNAL

Guanine nucleotide-binding protein G(olf) subunit alpha

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

2774

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2774

P38405

http://www.uniprot.org/uniprotkb/P38405/entry

14680

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14680

Q8CGK7

http://www.uniprot.org/uniprot/Q8CGK7

P38406

http://www.uniprot.org/uniprot/P38406

The antiserum was produced against synthesized peptide derived from human GNAL. AA range:41-90

Gα olf Polyclonal Antibody detects endogenous levels of Gα olf protein.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

40kD

-20°C/1 year

Polyclonal, Rabbit,IgG

G protein subunit alpha L(GNAL) Homo sapiens This gene encodes a stimulatory G protein alpha subunit which mediates odorant signaling in the olfactory epithelium. This protein couples dopamine type 1 receptors and adenosine A2A receptors and is widely expressed in the central nervous system. Mutations in this gene have been associated with dystonia 25 and this gene is located in a susceptibility region for bipolar disorder and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],

Detected in olfactory neuroepithelium, brain, testis, and to a lower extent in retina, lung alveoli, spleen. Trace amounts where seen in kidney, adrenal gland and liver. Found to be expressed in all the insulinomas examined.

plasma membrane,extracellular exosome,

Calcium;Olfactory transduction;

function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters.,similarity:Belongs to the G-alpha family. G(s) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.,tissue specificity:Detected in olfactory neuroepithelium, brain, testis, and to a lower extent in retina, lung alveoli, spleen. Trace amounts where seen in kidney, adrenal gland and liver. Found to be expressed in all the insulinomas examined.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.