产品名称
Gα 14 Rabbit Polyclonal Antibody
别名
GNA14; Guanine nucleotide-binding protein subunit alpha-14; G alpha-14; G-protein subunit alpha-14
蛋白名称
Guanine nucleotide-binding protein subunit alpha-14
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9630
Human Swissprot No.
O95837
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O95837/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14675
Mouse Swissprot No.
P30677
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P30677
免疫原
The antiserum was produced against synthesized peptide derived from human GNA14. AA range:1-50
特异性
Gα 14 Polyclonal Antibody detects endogenous levels of Gα 14 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the guanine nucleotide-binding, or G protein family. G proteins are heterotrimers consisting of alpha, beta and gamma subunits. The encoded protein is a member of the alpha family of G proteins, more specifically the alpha q subfamily of G proteins. The encoded protein may play a role in pertussis-toxin resistant activation of phospholipase C-beta and its downstream effectors.[provided by RefSeq, Feb 2009],
组织表达
Caudate nucleus,Pancreas,Spleen,
细胞定位
heterotrimeric G-protein complex,plasma membrane,extracellular exosome,
功能
function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.,similarity:Belongs to the G-alpha family. G(q) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
