产品名称
Gz-α Rabbit Polyclonal Antibody
别名
GNAZ; Guanine nucleotide-binding protein G(z) subunit alpha; G(x) alpha chain; Gz-alpha
蛋白名称
Guanine nucleotide-binding protein G(z) subunit alpha
反应种属
Human,Mouse,Rat,Monkey
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2781
Human Swissprot No.
P19086
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P19086/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14687
Mouse Swissprot No.
O70443
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O70443
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25740
Rat Swissprot Link
http://www.uniprot.org/uniprot/P19627
免疫原
The antiserum was produced against synthesized peptide derived from human Gz-alpha. AA range:1-50
特异性
Gz-α Polyclonal Antibody detects endogenous levels of Gz-α protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
G protein subunit alpha z(GNAZ) Homo sapiens The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms. This encoded protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids. [provided by RefSeq, Jul 2008],
细胞定位
Membrane; Lipid-anchor.
信号通路
Long-term depression;
功能
function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.,similarity:Belongs to the G-alpha family. G(i/o/t/z) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
