产品名称
GS28 Rabbit Polyclonal Antibody
别名
GOSR1; GS28; Golgi SNAP receptor complex member 1; 28 kDa Golgi SNARE protein; 28 kDa cis-Golgi SNARE p28; GOS-28
蛋白名称
Golgi SNAP receptor complex member 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9527
Human Swissprot No.
O95249
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O95249/entry
Mouse Swissprot No.
O88630
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O88630
免疫原
The antiserum was produced against synthesized peptide derived from human GOSR1. AA range:11-60
特异性
GS28 Polyclonal Antibody detects endogenous levels of GS28 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a trafficking membrane protein which transports proteins among the endoplasmic reticulum and the Golgi and between Golgi compartments. This protein is considered an essential component of the Golgi SNAP receptor (SNARE) complex. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
Colon carcinoma,Prostate,Testis,Umbilical cord blood,
细胞定位
Golgi apparatus membrane ; Single-pass type IV membrane protein . Localizes throughout the Golgi apparatus, with lowest levels in the trans-Golgi network (By similarity). Enriched on vesicular components at the terminal rims of the Golgi. Found in Golgi microtubules at low temperature (15 degrees Celsius). .
信号通路
SNARE interactions in vesicular transport;
功能
function:Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport.,similarity:Belongs to the GOSR1 family.,subcellular location:Enriched on vesicular components at the terminal rims of the Golgi.,subunit:Interacts with GABARAPL2. Identified in a unique SNARE complex composed of the Golgi SNAREs GOSR2, STX5 and YKT6.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
