产品名称
GPSN2 Rabbit Polyclonal Antibody
别名
TECR; GPSN2; SC2; Trans-2; 3-enoyl-CoA reductase; TER; Synaptic glycoprotein SC2
蛋白名称
Trans-2,3-enoyl-CoA reductase
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9524
Human Swissprot No.
Q9NZ01
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NZ01/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=106529
Mouse Swissprot No.
Q9CY27
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CY27
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=191576
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q64232
免疫原
The antiserum was produced against synthesized peptide derived from human GPSN2. AA range:259-308
特异性
GPSN2 Polyclonal Antibody detects endogenous levels of GPSN2 protein.
稀释度
WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:40000. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. The elongation of microsomal long and very long chain fatty acid consists of 4 sequential reactions. This protein catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Apr 2011],
组织表达
Expressed in most tissues tested. Highly expressed in skeletal muscle.
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
信号通路
Biosynthesis of unsaturated fatty acids;
功能
steroid biosynthetic process,?steroid metabolic process,?lipid biosynthetic process,?oxidation reduction,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.