产品名称
GPR75 Rabbit Polyclonal Antibody
别名
GPR75; Probable G-protein coupled receptor 75
蛋白名称
Probable G-protein coupled receptor 75
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10936
Human Swissprot No.
O95800
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O95800/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=237716
Mouse Swissprot No.
Q6X632
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6X632
免疫原
The antiserum was produced against synthesized peptide derived from human GPR75. AA range:381-430
特异性
GPR75 Polyclonal Antibody detects endogenous levels of GPR75 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.[supplied by OMIM, Jul 2002],
组织表达
Expressed at high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium. In situ hybridization of adult eye sections localized transcripts only to the perivascular cells, surrounding retinal arterioles, in the ganglion cell/nerve fiber layer. Also expressed by islet cells (at protein level).
细胞定位
Cell membrane; Multi-pass membrane protein .
功能
function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed at high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium. In situ hybridization of adult eye sections localized transcripts only to the perivascular cells, surrounding retinal arterioles, in the ganglion cell/nerve fiber layer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
