产品名称
GPR50 Rabbit Polyclonal Antibody
别名
GPR50; Melatonin-related receptor; G protein-coupled receptor 50; H9
蛋白名称
Melatonin-related receptor
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9248
Human Swissprot No.
Q13585
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q13585/entry
Mouse Swissprot No.
O88495
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O88495
免疫原
The antiserum was produced against synthesized peptide derived from human MTR1L. AA range:301-350
特异性
GPR50 Polyclonal Antibody detects endogenous levels of GPR50 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010],
组织表达
Hypothalamus and pituitary.
细胞定位
Cell membrane; Multi-pass membrane protein.
信号通路
Neuroactive ligand-receptor interaction;
功能
function:Does not bind melatonin.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Hypothalamus and pituitary.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
