产品名称
GPR48 Rabbit Polyclonal Antibody
别名
LGR4; GPR48; Leucine-rich repeat-containing G-protein coupled receptor 4; G-protein coupled receptor 48
蛋白名称
Leucine-rich repeat-containing G-protein coupled receptor 4
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55366
Human Swissprot No.
Q9BXB1
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9BXB1/entry
Mouse Swissprot No.
A2ARI4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/A2ARI4
免疫原
The antiserum was produced against synthesized peptide derived from human LGR4. AA range:461-510
特异性
GPR48 Polyclonal Antibody detects endogenous levels of GPR48 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a G-protein coupled receptor that binds R-spondins and activates the Wnt signaling pathway. This Wnt signaling pathway activation is necessary for proper development of many organs of the body. [provided by RefSeq, Oct 2016],
组织表达
Expressed in multiple steroidogenic tissues: placenta, ovary, testis and adrenal. Expressed also in spinal cord, thyroid, stomach, trachea, heart, pancreas, kidney, prostate and spleen.
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,similarity:Contains 15 LRR (leucine-rich) repeats.,tissue specificity:Expressed in multiple steroidogenic tissues: placenta, ovary, testis and adrenal. Expressed also in spinal cord, thyroid, stomach, trachea, heart, pancreas, kidney, prostate and spleen.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
