产品名称
GPR41 Rabbit Polyclonal Antibody
别名
FFAR3; GPR41; Free fatty acid receptor 3; G-protein coupled receptor 41
蛋白名称
Free fatty acid receptor 3
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2865
Human Swissprot No.
O14843
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O14843/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=233080
Mouse Swissprot No.
Q3UFD7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3UFD7
免疫原
The antiserum was produced against synthesized peptide derived from human FFAR3. AA range:11-60
特异性
GPR41 Polyclonal Antibody detects endogenous levels of GPR41 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Receptor for short chain fatty acids through a G(i)-protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Highest level in adipose tissue, and lower expression across all tissues tested.,
组织表达
Highest level in adipose tissue, and lower expression across all tissues tested. Expressed in sympathetic ganglia.
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
function:Receptor for short chain fatty acids through a G(i)-protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Highest level in adipose tissue, and lower expression across all tissues tested.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
