产品名称
GPR18 Rabbit Polyclonal Antibody
别名
GPR18; GPCRW; N-arachidonyl glycine receptor; NAGly receptor; G-protein coupled receptor 18
蛋白名称
N-arachidonyl glycine receptor
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2841
Human Swissprot No.
Q14330
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q14330/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=110168
Mouse Swissprot No.
Q8K1Z6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K1Z6
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=679957
Rat Swissprot Link
http://www.uniprot.org/uniprot/A1A5S3
免疫原
The antiserum was produced against synthesized peptide derived from human GPR18. AA range:191-240
特异性
GPR18 Polyclonal Antibody detects endogenous levels of GPR18 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Receptor for N-arachidonyl glycine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Most abundant in testis and spleen. Highly expressed in CD4 and CD8-positive T-cells as well as CD19-positive B-cells.,
组织表达
Expressed in midpiece of spermatozoon (at protein level) (PubMed:27572937). Most abundant in testis and spleen (PubMed:16844083). Highly expressed in CD4 and CD8-positive T-cells as well as CD19-positive B-cells (PubMed:16844083).
细胞定位
Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane .
功能
function:Receptor for N-arachidonyl glycine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Most abundant in testis and spleen. Highly expressed in CD4 and CD8-positive T-cells as well as CD19-positive B-cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
