产品名称
GPR172B Rabbit Polyclonal Antibody
别名
SLC52A1; GPR172B; PAR2; RFT1; Solute carrier family 52; riboflavin transporter, member 1; Porcine endogenous retrovirus A receptor 2; PERV-A receptor 2; Protein GPR172B; Riboflavin transporter 1; hRFT1
蛋白名称
Solute carrier family 52 riboflavin transporter member 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55065
Human Swissprot No.
Q9NWF4
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NWF4/entry
免疫原
The antiserum was produced against synthesized peptide derived from human PEVR2. AA range:235-284
特异性
GPR172B Polyclonal Antibody detects endogenous levels of GPR172B protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Biological redox reactions require electron donors and acceptor. Vitamin B2 is the source for the flavin in flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) which are common redox reagents. This gene encodes a member of the riboflavin (vitamin B2) transporter family. Haploinsufficiency of this protein can cause maternal riboflavin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2013],
组织表达
Widely expressed. Highly expressed in the testis, placenta and small intestine. Expressed at lower level in other tissues.
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
function:Acts as receptor for porcine endogenous retrovirus subgroup A (PERV-A).,similarity:Belongs to the PERVR family.,tissue specificity:Detected in a wide variety of tissues. High expression in testis.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
