产品名称
GPR17 Rabbit Polyclonal Antibody
别名
GPR17; Uracil nucleotide/cysteinyl leukotriene receptor; UDP/CysLT receptor; G-protein coupled receptor 17; P2Y-like receptor; R12
蛋白名称
Uracil nucleotide/cysteinyl leukotriene receptor
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2840
Human Swissprot No.
Q13304
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q13304/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=574402
Mouse Swissprot No.
Q6NS65
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6NS65
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=767613
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q09QM4
免疫原
The antiserum was produced against synthesized peptide derived from human GPR17. AA range:196-245
特异性
GPR17 Polyclonal Antibody detects endogenous levels of GPR17 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.,
组织表达
Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.
细胞定位
Cell membrane; Multi-pass membrane protein.
功能
function:Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
