产品名称
GPR133 Rabbit Polyclonal Antibody
别名
GPR133; PGR25; Probable G-protein coupled receptor 133; G-protein coupled receptor PGR25
蛋白名称
Probable G-protein coupled receptor 133
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=283383
Human Swissprot No.
Q6QNK2
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q6QNK2/entry
Mouse Swissprot No.
Q80T32
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q80T32
免疫原
The antiserum was produced against synthesized peptide derived from human GPR133. AA range:461-510
特异性
GPR133 Polyclonal Antibody detects endogenous levels of GPR133 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The adhesion G-protein-coupled receptors (GPCRs), including GPR133, are membrane-bound proteins with long N termini containing multiple domains. GPCRs, or GPRs, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins (summary by Bjarnadottir et al., 2004 [PubMed 15203201]).[supplied by OMIM, Nov 2010],
组织表达
Up-regulated in CD133(+) cell population of glioblastoma.
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
