产品名称
GPR126 Rabbit Polyclonal Antibody
别名
GPR126; DREG; VIGR; G-protein coupled receptor 126; Developmentally regulated G-protein-coupled receptor; Vascular inducible G protein-coupled receptor
蛋白名称
G-protein coupled receptor 126
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57211
Human Swissprot No.
Q86SQ4
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q86SQ4/entry
Mouse Swissprot No.
Q6F3F9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6F3F9
免疫原
The antiserum was produced against synthesized peptide derived from human GPR126. AA range:431-480
特异性
GPR126 Polyclonal Antibody detects endogenous levels of GPR126 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009],
组织表达
Expressed in placenta and to a lower extent in pancreas and liver. Detected in aortic endothelial cells but not in skin microvascular endothelial cells.
细胞定位
Cell membrane ; Multi-pass membrane protein . Detected on the cell surface of activated but not resting umbilical vein. .
功能
function:Orphan receptor.,polymorphism:Genetic variations in GPR126 influences stature as a quantitative trait (STQTL) [MIM:606255]. Adult height is an easily observable and highly heritable complex continuous trait. Because of this, it is a model trait for studying genetic influence on quantitative traits.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 CUB domain.,similarity:Contains 1 GPS domain.,similarity:Contains 1 pentaxin domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
