产品名称
GPR124 Rabbit Polyclonal Antibody
别名
GPR124; KIAA1531; TEM5; G-protein coupled receptor 124; Tumor endothelial marker 5
蛋白名称
G-protein coupled receptor 124
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25960
Human Swissprot No.
Q96PE1
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q96PE1/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=78560
Mouse Swissprot No.
Q91ZV8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q91ZV8
免疫原
The antiserum was produced against synthesized peptide derived from human GPR124. AA range:1151-1200
特异性
GPR124 Polyclonal Antibody detects endogenous levels of GPR124 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
caution:It is uncertain whether Met-1 or Met-8 is the initiator.,domain:Binds to DLG1 through its PDZ-binding motif.,function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 5 LRR (leucine-rich) repeats.,subunit:Interacts with DLG1.,tissue specificity:Expressed in endothelial cells (at protein level). Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon.,
组织表达
Expressed in endothelial cells (at protein level) (PubMed:15021905, PubMed:16982628). Abundantly expressed in heart, placenta, ovary, small intestine, and colon (PubMed:15021905).
细胞定位
Cell membrane ; Multi-pass membrane protein . Cell projection, filopodium . Enriched at lateral cell borders and also at sites of cell-ECM (extracellular matrix) contact. .
功能
caution:It is uncertain whether Met-1 or Met-8 is the initiator.,domain:Binds to DLG1 through its PDZ-binding motif.,function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 5 LRR (leucine-rich) repeats.,subunit:Interacts with DLG1.,tissue specificity:Expressed in endothelial cells (at protein level). Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
