产品名称
GPR10 Rabbit Polyclonal Antibody
别名
PRLHR; GPR10; GR3; Prolactin-releasing peptide receptor; PrRP receptor; PrRPR; G-protein coupled receptor 10; hGR3
蛋白名称
Prolactin-releasing peptide receptor
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2834
Human Swissprot No.
P49683
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P49683/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=226278
Mouse Swissprot No.
Q6VMN6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6VMN6
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=246075
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q64121
免疫原
The antiserum was produced against synthesized peptide derived from human PRLHR. AA range:184-233
特异性
GPR10 Polyclonal Antibody detects endogenous levels of GPR10 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
PRLHR is a 7-transmembrane domain receptor for prolactin-releasing hormone (PRLH; MIM 602663) that is highly expressed in anterior pituitary (Ozawa et al., 2002 [PubMed 11923475]).[supplied by OMIM, Mar 2008],
组织表达
Only detected in the pituitary gland and in all cell types of pituitary adenomas.
细胞定位
Cell membrane; Multi-pass membrane protein.
信号通路
Neuroactive ligand-receptor interaction;
功能
function:Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing.,induction:Repressed by bromocriptine, a dopamine agonist.,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts through its C-terminal region with the PDZ domain-containing proteins GRIP1, GRIP2 and PICK1. Interacts with PDZ domains 4 and 5 of GRIP1 and with the PDZ domain of PICK1.,tissue specificity:Only detected in the pituitary gland and in all cell types of pituitary adenomas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
