产品名称
GNL1 Rabbit Polyclonal Antibody
别名
GNL1; HSR1; Guanine nucleotide-binding protein-like 1; GTP-binding protein HSR1
蛋白名称
Guanine nucleotide-binding protein-like 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2794
Human Swissprot No.
P36915
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P36915/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14670
Mouse Swissprot No.
P36916
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P36916
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=309593
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q6MG06
免疫原
The antiserum was produced against synthesized peptide derived from human GNL1. AA range:61-110
特异性
GNL1 Polyclonal Antibody detects endogenous levels of GNL1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The GNL1 gene, identified in the human major histocompatibility complex class I region, shows a high degree of similarity with its mouse counterpart. The GNL1 gene is located less than 2 kb centromeric to HLA-E, in the same transcriptional orientation. GNL1 is telomeric to HLA-B and HLA-C. [provided by RefSeq, Jul 2008],
组织表达
Cervix,Muscle,Peripheral blood leukocyte,Skin,T-cell,
细胞定位
extracellular space,nucleus,
功能
domain:In contrast to other GTP-binding proteins, this family is characterized by a circular permutation of the GTPase motifs described by a G4-G1-G3 pattern.,function:Possible regulatory or functional link with the histocompatibility cluster.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the MMR1/HSR1 GTP-binding protein family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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