产品名称
Glypican-5 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2262
Human Swissprot No.
P78333
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P78333/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=103978
Mouse Swissprot No.
Q8CAL5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8CAL5
免疫原
Synthesized peptide derived from the Internal region of human Glypican-5.
特异性
Glypican-5 Polyclonal Antibody detects endogenous levels of Glypican-5 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq, Jul 2008],
组织表达
In adult, primarily expressed in the brain. Also detected in fetal brain, lung and liver.
细胞定位
Cell membrane ; Lipid-anchor, GPI-anchor ; Extracellular side .; [Secreted glypican-5]: Secreted, extracellular space .
功能
function:Cell surface proteoglycan that bears heparan sulfate.,similarity:Belongs to the glypican family.,tissue specificity:In adult, primarily expressed in the brain. Also detected in fetal brain, lung and liver.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.