BD-PT1916

GLP-1R Rabbit Polyclonal Antibody

GLP1R; Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R

常规抗体

GLP1R

Glucagon-like peptide 1 receptor

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

2740

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2740

P43220

http://www.uniprot.org/uniprotkb/P43220/entry

O35659

http://www.uniprot.org/uniprot/O35659

The antiserum was produced against synthesized peptide derived from human GLP1R. AA range:101-150

GLP-1R Polyclonal Antibody detects endogenous levels of GLP-1R protein.

WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

53kD

-20°C/1 year

Polyclonal, Rabbit,IgG

glucagon like peptide 1 receptor(GLP1R) Homo sapiens This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016],

Gastric carcinoma,Insulinoma,Pancreas,Pancreatic islet,Placenta,

Cell membrane ; Multi-pass membrane protein .

Neuroactive ligand-receptor interaction;

function:This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,online information:Glucagon-like peptide 1 entry,similarity:Belongs to the G-protein coupled receptor 2 family.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.