BD-PT1898

GGH Rabbit Polyclonal Antibody

GGH; Gamma-glutamyl hydrolase; Conjugase; GH; Gamma-Glu-X carboxypeptidase

常规抗体

GGH

Gamma-glutamyl hydrolase

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

8836

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8836

Q92820

http://www.uniprot.org/uniprotkb/Q92820/entry

Q9Z0L8

http://www.uniprot.org/uniprot/Q9Z0L8

The antiserum was produced against synthesized peptide derived from human GGH. AA range:251-300

GGH Polyclonal Antibody detects endogenous levels of GGH protein.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

36kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate. [provided by RefSeq, Jul 2008],

Skin,

Secreted, extracellular space . Lysosome . Melanosome . While its intracellular location is primarily the lysosome, most of the enzyme activity is secreted. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .

Folate biosynthesis;

catalytic activity:Hydrolysis of a gamma-glutamyl bond.,function:Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.,similarity:Belongs to the peptidase C26 family.,similarity:Contains 1 gamma-glutamyl hydrolase domain.,subcellular location:While its intracellular location is primarily the lysosome, most of the enzyme activity is secreted. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.