产品名称
GDF-9 Rabbit Polyclonal Antibody
别名
GDF9; Growth/differentiation factor 9; GDF-9
蛋白名称
Growth/differentiation factor 9
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2661
Human Swissprot No.
O60383
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O60383/entry
Mouse Swissprot No.
Q07105
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q07105
免疫原
The antiserum was produced against synthesized peptide derived from human GDF-9. AA range:273-322
特异性
GDF-9 Polyclonal Antibody detects endogenous levels of GDF-9 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates ovarian function. Reduced expression of this gene may be associated with polycystic ovary syndrome and mutations in this gene may be more common in mothers of dizygotic twins. [provided by RefSeq, Jul 2016],
组织表达
Expressed in ovarian granulosa cells. Present in oocytes of primary follicles (at protein level).
功能
function:Required for ovarian folliculogenesis.,similarity:Belongs to the TGF-beta family.,subunit:Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
