产品名称
GBP4 Rabbit Polyclonal Antibody
别名
GBP4; Guanylate-binding protein 4; GTP-binding protein 4; GBP-4; Guanine nucleotide-binding protein 4
蛋白名称
Guanylate-binding protein 4
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=115361
Human Swissprot No.
Q96PP9
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q96PP9/entry
Mouse Swissprot No.
Q61107
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q61107
免疫原
The antiserum was produced against synthesized peptide derived from human GBP4. AA range:551-600
特异性
GBP4 Polyclonal Antibody detects endogenous levels of GBP4 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal, 2005 [PubMed 16108726]).[supplied by OMIM, Dec 2008],
组织表达
Brain,Epithelium,Placenta,Spinal cord,Spleen,Testis,
细胞定位
Cytoplasm . Nucleus . Cytoplasm, perinuclear region . Golgi apparatus membrane . Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus. .
功能
function:Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation.,similarity:Belongs to the GBP family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
