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GBP3 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT1868
产品名称
GBP3 Rabbit Polyclonal Antibody
别名
GBP3; Guanylate-binding protein 3; GTP-binding protein 3; GBP-3; Guanine nucleotide-binding protein 3
类别
常规抗体
基因名称
GBP3
蛋白名称
Guanylate-binding protein 3
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
2635
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2635
Human Swissprot No.
Q9H0R5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9H0R5/entry
免疫原
The antiserum was produced against synthesized peptide derived from human GBP3. AA range:481-530
特异性
GBP3 Polyclonal Antibody detects endogenous levels of GBP3 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
预测分子量
64kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the guanylate-binding protein (GBP) family. GBPs specifically bind guanine nucleotides (GMP, GDP, and GTP) and contain two of the three consensus motifs found in typical GTP-binding proteins. The encoded protein interacts with a member of the germinal center kinase family. Multiple transcript variants encoding different isoforms have been been found for this gene. [provided by RefSeq, Jan 2016],
组织表达
Brain,Prostate,
细胞定位
Cytoplasm . Cytoplasm, perinuclear region . Golgi apparatus membrane . Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus. .
功能
function:Binds GTP, GDP and GMP.,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Unlikely isoform. Aberrant splice sites.,similarity:Belongs to the GBP family.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from HT-29 and COLO cells, using GBP3 Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using GBP3 Polyclonal Antibody

Western Blot analysis of COLO205 cells using GBP3 Polyclonal Antibody

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