产品名称
GBP3 Rabbit Polyclonal Antibody
别名
GBP3; Guanylate-binding protein 3; GTP-binding protein 3; GBP-3; Guanine nucleotide-binding protein 3
蛋白名称
Guanylate-binding protein 3
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2635
Human Swissprot No.
Q9H0R5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9H0R5/entry
免疫原
The antiserum was produced against synthesized peptide derived from human GBP3. AA range:481-530
特异性
GBP3 Polyclonal Antibody detects endogenous levels of GBP3 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the guanylate-binding protein (GBP) family. GBPs specifically bind guanine nucleotides (GMP, GDP, and GTP) and contain two of the three consensus motifs found in typical GTP-binding proteins. The encoded protein interacts with a member of the germinal center kinase family. Multiple transcript variants encoding different isoforms have been been found for this gene. [provided by RefSeq, Jan 2016],
细胞定位
Cytoplasm . Cytoplasm, perinuclear region . Golgi apparatus membrane . Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus. .
功能
function:Binds GTP, GDP and GMP.,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Unlikely isoform. Aberrant splice sites.,similarity:Belongs to the GBP family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.